Planetary Health and Traditional Medicine: A Potential Synergistic Approach to Tackle Antimicrobial Resistance

Antimicrobials are compounds that impede the activities of bacteria, viruses, parasites, or fungi. Continuous antimicrobial overuse, misuse, and improper use for human, animal, agricultural purposes raising concerns about antibiotic residue pollution in environment, resistance genes (ARGs). Because antimicrobial-resistant diseases linked to human–-microbial ecosystems, environmental from ARGs alters makeup diversity human gut microbiota, putting under selection pressure. This perspective proposes antibiotic-induced microbiome depletion is quality has repercussions health via microbiome’s sensitive ecosystem. stimulated new global efforts multidisciplinary, integrative approaches addressing Antimicrobial Resistance (AMR) awareness communities. Several academic papers published recent years have shown medicinal plant extracts effective against on WHO’s pathogen priority lists (PPL), such as ESKAPE pathogens (Enterococcus faecium, Staphylococcus aureus, Klebsiella pneumoniae, Acinetobacter baumannii, Pseudomonas aeruginosa, Enterobacter species). Traditional medicine, with its knowledge plants, promises be a valuable source next-generation powerful antimicrobials. Examples include discovery Artemisinin, highly active antimalarial drug derived Artemisia annua, Taxol, an chemotherapeutic bark Pacific yew, Taxus brevifolia. The connections between small large ecosystems’ vitality, biodiversity protection, been acknowledged by Planetary Health principles. To address these intertwined concerns, Medicine approach can adopted, addressed expanding screening plants bioactive compounds.